Receiving access denied error from Visual Studio when trying to change target framework

Question

The error reads,

TargetFrameworkMoniker: An error occurred saving the project file 'yadayada.csproj'. Access is denied.

I'm trying to switch from .net 3.5 to .net 4.0 or higher.

The project is hooked into TFS in Visual Studio 2010 (also tried VS 2013, same error). I'm in a VM environment.

Any clues about this error? Google returns very little information. It seems like I have proper access to the file, but how is VS accessing it?

Answer 1

I have found that if you get the error, hit save, close visual studio and reopen the project you will find that 86.5% of the time the setting was changed.