Any hints on the required configuration changes (if at all this is possible) will be very helpful.
This might be of interest to you http://www.codeplex.com/SharePointMVC
I published it about 5 minutes ago.
It is basically a library to help rendering ASP.MVC inside a SharePoint masterpage.
Still early days but you get the idea.
You're going to have a hoot of a time de-inheriting everything (modules, handlers, assemblies, namespaces) in the MVC app's web.config. I would recommend that instead of trying to get MVC working inside of the same IIS web site, why not just run your app outside of SharePoint? Joel Oleson just blogged about using "widgets" or "web parts" as a form of SharePoint integration:
Joel Oleson
I have heard from the MS MVC team that there is no plans for Sharepoint to use MVC. However MVC can be used with Sharepoint with a few tweaks
The following sharepoint site, www.themedicinecabinet.co.uk, was built using ASP.net MVC 2.
This article explains how this was done http://vspug.com/mbailey/files/2010/04/Using-ASP.NET-MVC-2-with-Sharepoint-Publishing.pdf
We've just released an opensource project that let's you use SharePoint 2010 as the backend of a site and use ASP.NET MVC3 on the frontend. We've been using the code base for the last two years and wanted to share it with the community since we're confident others would find it useful.
Documentation is still sparse - please feel free to reach out if you have any questions or need help.
http://www.slamcms.com
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