Why Should I Use Them? The main benefit to using data URIs is that you can reduce the number of HTTP requests that your site needs to make to load the page. Each individual file referenced in your CSS or HTML code will create a new HTTP request.
The HTML5 <audio> and <video> tags make it simple to add media to a website. You need to set src attribute to identify the media source and include a controls attribute so the user can play and pause the media.
These are my test results. I'll try with Ogg as well if prompted.
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Test results
IE9 supports this, but only for file formats it supports. For instance, it works for MP3 files but it will not work for WAV files. Tried http://www.themaninblue.com/experiment/JS-909/ and the following test:
<!DOCTYPE html>
<html>
<head>
</head>
<body>
<audio controls="controls" autobuffer="autobuffer" autoplay="autoplay">
<source src="data:audio/wav;base64,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" />
</audio>
</body>
</html>
It should be possible, except in IE8 and below, which does not support Audio/Video elements. Note that Opera does limit the size of the URI.
That's probably because IE9 doesn't support WAV format in its audio element. Only MP3 is supported by now. I really hope that they change that in the RTM version.
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