Will Microsoft Edge use prefixes like -webkit- or -ms-?

Question

Will Microsoft Edge use prefixes like -webkit-, -ms-, or its own new prefix for future functions? Something like -me-, perhaps?

Answer 1

tl;dr: Yes and No

Existing prefixed properties that are hugely popular will remain until they have native support, but Microsoft Edge will not be introducing a new prefix system for features. Instead, they'll use feature flags (like Chrome and Firefox for experimental features on the client side, rather than the developer side).

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Direct Source

Some of the more notable removals are those where Microsoft Edge supports the latest standard API definition and removes support for MS prefixed versions of the APIs. Examples include CSS Transforms, Fullscreen API, and Pointer Events. This brings up an important topic: vendor prefixes. You’ll see a trend in the vendor prefixes in Microsoft Edge compared to IE:

Our support (or lack thereof) of prefixed APIs is data-driven with compatibility as the sole purpose for any that remain. As examples, -webkit-border-radius is still in use on over 60% of page loads and the MS-prefixed Encrypted Media Extensions APIs are still in use on top video streaming services. Because of the impact on interoperability across the Web, these are supported in Microsoft Edge for the time being.

The consensus across the industry is that vendor prefixes cause more harm than good and the necessity of browsers supporting other vendor’s prefixes is a good example of why. Going forward, we’re using feature flags (accessible by navigating to about:flags) to introduce experimental APIs and minting new vendor prefixed APIs sparingly, if ever. Today, you’ll find examples like early implementations of CSS Filters, Touch Events, and HTML5 date inputs in about:flags. We’re also working with other browser vendors on exploring new approaches to experimental APIs that enable easier and broader access to experimental APIs while minimizing the compatibility burden that prefixes incur. Check out this talk (starts around 31 min mark) for an initial proposal we’ve made, tentatively named “API Trials”.

(Emphasis mine)

Answer 2

A detailed list of WebKit properties supported in Microsoft Edge is available here: https://msdn.microsoft.com/en-us/library/mt270097%28v=vs.85%29.aspx