I read that a few databases can be used in-memory but can't think of reason why someone would want to use this feature. I always use a database to persist data and memory caches for fast access.
The in-memory database defined In-memory data stores are designed to enable minimal response times by eliminating the need to access disks. Because all data is stored and managed exclusively in main memory, in-memory databases risk losing data upon a process or server failure.
An in-memory database system streamlines processing by eliminating multiple data transfers, reduces memory consumption by removing multiple copies of data, and simplifies processing by minimizing CPU demands.
Cons of in-memory databases The use of an RAM means faster access on the one hand, but also brings with it a key disadvantage: the data stored is only temporary. If the computer system should crash, all temporarily-stored data would be lost.
Cache is also a kind of database, like a file system is. 'Memory cache' is just a specific application of an in-memory database and some in-memory databases are specialized as memory caches.
Other uses of in-memory databases have already been included in other answers, but let me enumerate the uses too:
A common use case is to run unit/integration tests.
You don't really care about persisting data between each test run and you want tests to run as quickly as possible (to encourage people to do them often). Hosting a database in process gives you very quick access to the data.
Does your memory cache have SQL support?
How about you consider the in-memory database as a really clever cache?
That does leave questions of how the in-memory database gets populated and how updated are managed and consistency is preserved across multiple instances.
Searching for something among 100000 elements is slow if you don't use tricks like indexes. Those tricks are already implemented in a database engine (be it persistent or in-memory).
A in-memory database might offer a more efficient search feature than what you might be able to implement yourself quickly over self-written structures.
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