So, with iOS 6 an UITextView can take an attributedString, which could be useful for Syntax highlighting.
I'm doing some regex patterns in -textView:shouldChangeTextInRange:replacementText: and oftentimes I need to change the color of a word already typed. I see no other options than resetting the attributedText, which takes time.
- (BOOL)textView:(UITextView *)textView shouldChangeTextInRange:(NSRange)range replacementText:(NSString *)text
{
    //A context will allow us to not call -attributedText on the textView, which is slow.
    //Keep context up to date
    [self.context replaceCharactersInRange:range withAttributedString:[[NSAttributedString alloc] initWithString:text attributes:self.textView.typingAttributes]];
    // […]
    self.textView.scrollEnabled = FALSE;
    [self.context setAttributes:self.defaultStyle range:NSMakeRange(0, self.context.length)];
    [self refresh]; //Runs regex-patterns in the context
    textView.attributedText = self.context;
    self.textView.selectedRange = NSMakeRange(range.location + text.length, 0);
    self.textView.scrollEnabled = TRUE;
    return FALSE;
}
This runs okayish on the simulator, but on an iPad 3 each -setAttributedText takes a few hundreds of milliseconds.
I filed a bug to Apple, with the request of being able to mutate the attributedText. It got marked as a duplicate, so I cannot see what they're saying about this.
The more specific question:
How can I change the color of certain ranges in a UITextView, with a large multicolored text, with good enough performance to do it in every shouldReplaceText...?
The more broad question: How do you do syntax highlighting with a UITextView in iOS 6?
I encountered the same problem for my application Zap-Guitar (No-Strings-Attached) where I allow users to type/paste/edit their own songs and the app highlights recognized chords.
Yes it is true apple uses an html writer and parser to display the attributed text. A wonderful explanation of behind the scene can be found here: http://www.cocoanetics.com/2012/12/uitextview-caught-with-trousers-down/
The only solution I found for this problem is not to use attributed text which is an overkill for syntax highlighting.
Instead I reverted to the good old UITextView with plain text and added buttons to the text view where highlighted was needed. To compute the buttons frames I used this answer: How to find position or get rect of any word in textview and place buttons over that?
This reduced CPU usage by 30% (give or take).
Here is a handy category:
@implementation UITextView (WithButtons)
- (CGRect)frameForTextRange:(NSRange)range {
    UITextPosition *beginning = self.beginningOfDocument;
    UITextPosition *start = [self positionFromPosition:beginning offset:range.location];
    UITextPosition *end = [self positionFromPosition:start offset:range.length];
    UITextRange *textRange = [self textRangeFromPosition:start toPosition:end];
    CGRect rect = [self firstRectForRange:textRange];
    return [self convertRect:rect fromView:self.textInputView];
}
@end
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