I have a Ruby program that loads up two very large yaml files, so I can get some speed-up by taking advantage of the multiple cores by forking off some processes. I've tried looking, but I'm having trouble figuring how, or even if, I can share variables in different processes.
The following code is what I currently have:
@proteins = ""
@decoyProteins = "" 
fork do
  @proteins = YAML.load_file(database)
  exit
end
fork do
  @decoyProteins = YAML.load_file(database)
  exit
end
p @proteins["LVDK"]
P displays nil though because of the fork.
So is it possible to have the forked processes share the variables? And if so, how?
One problem is you need to use Process.wait to wait for your forked processes to complete.  The other is that you can't do interprocess communication through variables.  To see this:
@one = nil
@two = nil
@hash = {}
pidA = fork do
    sleep 1
    @one = 1
    @hash[:one] = 1
    p [:one, @one, :hash, @hash] #=> [ :one, 1, :hash, { :one => 1 } ]
end
pidB = fork do
    sleep 2
    @two = 2
    @hash[:two] = 2
    p [:two, @two, :hash, @hash] #=> [ :two, 2, :hash, { :two => 2 } ]
end
Process.wait(pidB)
Process.wait(pidA)
p [:one, @one, :two, @two, :hash, @hash] #=> [ :one, nil, :two, nil, :hash, {} ]
One way to do interprocess communication is using a pipe (IO::pipe).  Open it before you fork, then have each side of the fork close one end of the pipe.
From ri IO::pipe:
    rd, wr = IO.pipe
    if fork
      wr.close
      puts "Parent got: <#{rd.read}>"
      rd.close
      Process.wait
    else
      rd.close
      puts "Sending message to parent"
      wr.write "Hi Dad"
      wr.close
    end
 _produces:_
    Sending message to parent
    Parent got: <Hi Dad>
If you want to share variables, use threads:
@one = nil
@two = nil
@hash = {}
threadA = Thread.fork do
    sleep 1
    @one = 1
    @hash[:one] = 1
    p [:one, @one, :hash, @hash] #=> [ :one, 1, :hash, { :one => 1 } ] # (usually)
end
threadB = Thread.fork do
    sleep 2
    @two = 2
    @hash[:two] = 2
    p [:two, @two, :hash, @hash] #=> [ :two, 2, :hash, { :one => 1, :two => 2 } ] # (usually)
end
threadA.join
threadB.join
p [:one, @one, :two, @two, :hash, @hash] #=> [ :one, 1, :two, 2, :hash, { :one => 1, :two => 2 } ]
However, I'm not sure if threading will get you any gain when you're IO bound.
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