Permission Denied when running Mac app after upgrading to XCode 4.4

I had a working Mac application until I updated to XCode 4.4 and Mountain Lion. Now the application still compiles, but when I try to run it I get an error message.

error: failed to launch '/Users/username/James/mac/Browser/trunk/Browser/DerivedData/Browser/Build/Products/Debug/Browser.app/Contents/MacOS/Browser' -- Permission denied*

Can anybody explain why I might be getting this?

How do I give my Mac an application permission?

If you later decide to give a denied app access to your Mac, choose Apple menu > System Preferences, click Security & Privacy , click Privacy, click Accessibility, then select the app's checkbox.

I found this on an iPhone 5 (iOS 6.0) newly set up for development. I had to manually launch the app on the phone, and it said "Are you sure you want to launch this app signed by this devloper?" Once I approved that, the "permission denied" went away and it now launches from Xcode.