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Get MIME type from filename extension

Tags:

c#

asp.net

mime

People also ask

What is a MIME file extension?

MIME (Multipurpose Internet Mail Extensions) is an extension of the original Simple Mail Transport Protocol (SMTP) email protocol. It lets users exchange different kinds of data files, including audio, video, images and application programs, over email.

Is MIME type same as extension?

Slightly longer answer: Mime types and file extensions provide hints to how to deal with a file. Whereas file extensions are commonly used for your OS to decide what program to open a file with, Mime types are used by your browser to decide how to present some data (or the server on how to interpret received data).

Does every file have a MIME type?

There are too many issues with MIME types on different operating systems, different applications saving files differently, some files not having a MIME at all, and lastly, the fact that the extension and MIME could be altered by a malicious user or program.


For ASP.NET or other

The options were changed a bit in ASP.NET Core, here they are (credits):

  • new FileExtensionContentTypeProvider().TryGetContentType(fileName, out contentType); (vNext only)
    • Never tested, but looks like you can officially expand the mime types list via the exposed Mappings property.
  • Use the MimeTypes NuGet package
  • Copy the MimeMappings file from the reference source of the .NET Framework

For .NET Framework >= 4.5:

Use the System.Web.MimeMapping.GetMimeMapping method, that is part of the BCL in .NET Framework 4.5:

string mimeType = MimeMapping.GetMimeMapping(fileName);

If you need to add custom mappings you probably can use reflection to add mappings to the BCL MimeMapping class, it uses a custom dictionary that exposes this method, so you should invoke the following to add mappings (never tested tho, but should prob. work).

Anyway, when using reflection to add MIME types, be aware that since you're accessing a private field, its name might change or even be totally removed, so you should be extra cautious and add double checks and provide fail safe action for every step.

MimeMapping._mappingDictionary.AddMapping(string fileExtension, string mimeType)

UPDATE

For up-to-date mapping with additions from many contributors, see this GitHub repository:

https://github.com/samuelneff/MimeTypeMap

and NuGet package

https://www.nuget.org/packages/MimeTypeMapOfficial/


I've found many mime types my application uses are not in the default Windows registry and others are in the registry but not in the list included with IIS. I've compiled a list from these locations and added a few others that we use.

EDIT: See most up-do-date version with contributions here, including an efficient and deterministic two-way mapping.

private static IDictionary<string, string> _mappings = new Dictionary<string, string>(StringComparer.InvariantCultureIgnoreCase) {

        #region Big freaking list of mime types
        // combination of values from Windows 7 Registry and 
        // from C:\Windows\System32\inetsrv\config\applicationHost.config
        // some added, including .7z and .dat
        {".323", "text/h323"},
        {".3g2", "video/3gpp2"},
        {".3gp", "video/3gpp"},
        {".3gp2", "video/3gpp2"},
        {".3gpp", "video/3gpp"},
        {".7z", "application/x-7z-compressed"},
        {".aa", "audio/audible"},
        {".AAC", "audio/aac"},
        {".aaf", "application/octet-stream"},
        {".aax", "audio/vnd.audible.aax"},
        {".ac3", "audio/ac3"},
        {".aca", "application/octet-stream"},
        {".accda", "application/msaccess.addin"},
        {".accdb", "application/msaccess"},
        {".accdc", "application/msaccess.cab"},
        {".accde", "application/msaccess"},
        {".accdr", "application/msaccess.runtime"},
        {".accdt", "application/msaccess"},
        {".accdw", "application/msaccess.webapplication"},
        {".accft", "application/msaccess.ftemplate"},
        {".acx", "application/internet-property-stream"},
        {".AddIn", "text/xml"},
        {".ade", "application/msaccess"},
        {".adobebridge", "application/x-bridge-url"},
        {".adp", "application/msaccess"},
        {".ADT", "audio/vnd.dlna.adts"},
        {".ADTS", "audio/aac"},
        {".afm", "application/octet-stream"},
        {".ai", "application/postscript"},
        {".aif", "audio/x-aiff"},
        {".aifc", "audio/aiff"},
        {".aiff", "audio/aiff"},
        {".air", "application/vnd.adobe.air-application-installer-package+zip"},
        {".amc", "application/x-mpeg"},
        {".application", "application/x-ms-application"},
        {".art", "image/x-jg"},
        {".asa", "application/xml"},
        {".asax", "application/xml"},
        {".ascx", "application/xml"},
        {".asd", "application/octet-stream"},
        {".asf", "video/x-ms-asf"},
        {".ashx", "application/xml"},
        {".asi", "application/octet-stream"},
        {".asm", "text/plain"},
        {".asmx", "application/xml"},
        {".aspx", "application/xml"},
        {".asr", "video/x-ms-asf"},
        {".asx", "video/x-ms-asf"},
        {".atom", "application/atom+xml"},
        {".au", "audio/basic"},
        {".avi", "video/x-msvideo"},
        {".axs", "application/olescript"},
        {".bas", "text/plain"},
        {".bcpio", "application/x-bcpio"},
        {".bin", "application/octet-stream"},
        {".bmp", "image/bmp"},
        {".c", "text/plain"},
        {".cab", "application/octet-stream"},
        {".caf", "audio/x-caf"},
        {".calx", "application/vnd.ms-office.calx"},
        {".cat", "application/vnd.ms-pki.seccat"},
        {".cc", "text/plain"},
        {".cd", "text/plain"},
        {".cdda", "audio/aiff"},
        {".cdf", "application/x-cdf"},
        {".cer", "application/x-x509-ca-cert"},
        {".chm", "application/octet-stream"},
        {".class", "application/x-java-applet"},
        {".clp", "application/x-msclip"},
        {".cmx", "image/x-cmx"},
        {".cnf", "text/plain"},
        {".cod", "image/cis-cod"},
        {".config", "application/xml"},
        {".contact", "text/x-ms-contact"},
        {".coverage", "application/xml"},
        {".cpio", "application/x-cpio"},
        {".cpp", "text/plain"},
        {".crd", "application/x-mscardfile"},
        {".crl", "application/pkix-crl"},
        {".crt", "application/x-x509-ca-cert"},
        {".cs", "text/plain"},
        {".csdproj", "text/plain"},
        {".csh", "application/x-csh"},
        {".csproj", "text/plain"},
        {".css", "text/css"},
        {".csv", "text/csv"},
        {".cur", "application/octet-stream"},
        {".cxx", "text/plain"},
        {".dat", "application/octet-stream"},
        {".datasource", "application/xml"},
        {".dbproj", "text/plain"},
        {".dcr", "application/x-director"},
        {".def", "text/plain"},
        {".deploy", "application/octet-stream"},
        {".der", "application/x-x509-ca-cert"},
        {".dgml", "application/xml"},
        {".dib", "image/bmp"},
        {".dif", "video/x-dv"},
        {".dir", "application/x-director"},
        {".disco", "text/xml"},
        {".dll", "application/x-msdownload"},
        {".dll.config", "text/xml"},
        {".dlm", "text/dlm"},
        {".doc", "application/msword"},
        {".docm", "application/vnd.ms-word.document.macroEnabled.12"},
        {".docx", "application/vnd.openxmlformats-officedocument.wordprocessingml.document"},
        {".dot", "application/msword"},
        {".dotm", "application/vnd.ms-word.template.macroEnabled.12"},
        {".dotx", "application/vnd.openxmlformats-officedocument.wordprocessingml.template"},
        {".dsp", "application/octet-stream"},
        {".dsw", "text/plain"},
        {".dtd", "text/xml"},
        {".dtsConfig", "text/xml"},
        {".dv", "video/x-dv"},
        {".dvi", "application/x-dvi"},
        {".dwf", "drawing/x-dwf"},
        {".dwp", "application/octet-stream"},
        {".dxr", "application/x-director"},
        {".eml", "message/rfc822"},
        {".emz", "application/octet-stream"},
        {".eot", "application/octet-stream"},
        {".eps", "application/postscript"},
        {".etl", "application/etl"},
        {".etx", "text/x-setext"},
        {".evy", "application/envoy"},
        {".exe", "application/octet-stream"},
        {".exe.config", "text/xml"},
        {".fdf", "application/vnd.fdf"},
        {".fif", "application/fractals"},
        {".filters", "Application/xml"},
        {".fla", "application/octet-stream"},
        {".flr", "x-world/x-vrml"},
        {".flv", "video/x-flv"},
        {".fsscript", "application/fsharp-script"},
        {".fsx", "application/fsharp-script"},
        {".generictest", "application/xml"},
        {".gif", "image/gif"},
        {".group", "text/x-ms-group"},
        {".gsm", "audio/x-gsm"},
        {".gtar", "application/x-gtar"},
        {".gz", "application/x-gzip"},
        {".h", "text/plain"},
        {".hdf", "application/x-hdf"},
        {".hdml", "text/x-hdml"},
        {".hhc", "application/x-oleobject"},
        {".hhk", "application/octet-stream"},
        {".hhp", "application/octet-stream"},
        {".hlp", "application/winhlp"},
        {".hpp", "text/plain"},
        {".hqx", "application/mac-binhex40"},
        {".hta", "application/hta"},
        {".htc", "text/x-component"},
        {".htm", "text/html"},
        {".html", "text/html"},
        {".htt", "text/webviewhtml"},
        {".hxa", "application/xml"},
        {".hxc", "application/xml"},
        {".hxd", "application/octet-stream"},
        {".hxe", "application/xml"},
        {".hxf", "application/xml"},
        {".hxh", "application/octet-stream"},
        {".hxi", "application/octet-stream"},
        {".hxk", "application/xml"},
        {".hxq", "application/octet-stream"},
        {".hxr", "application/octet-stream"},
        {".hxs", "application/octet-stream"},
        {".hxt", "text/html"},
        {".hxv", "application/xml"},
        {".hxw", "application/octet-stream"},
        {".hxx", "text/plain"},
        {".i", "text/plain"},
        {".ico", "image/x-icon"},
        {".ics", "application/octet-stream"},
        {".idl", "text/plain"},
        {".ief", "image/ief"},
        {".iii", "application/x-iphone"},
        {".inc", "text/plain"},
        {".inf", "application/octet-stream"},
        {".inl", "text/plain"},
        {".ins", "application/x-internet-signup"},
        {".ipa", "application/x-itunes-ipa"},
        {".ipg", "application/x-itunes-ipg"},
        {".ipproj", "text/plain"},
        {".ipsw", "application/x-itunes-ipsw"},
        {".iqy", "text/x-ms-iqy"},
        {".isp", "application/x-internet-signup"},
        {".ite", "application/x-itunes-ite"},
        {".itlp", "application/x-itunes-itlp"},
        {".itms", "application/x-itunes-itms"},
        {".itpc", "application/x-itunes-itpc"},
        {".IVF", "video/x-ivf"},
        {".jar", "application/java-archive"},
        {".java", "application/octet-stream"},
        {".jck", "application/liquidmotion"},
        {".jcz", "application/liquidmotion"},
        {".jfif", "image/pjpeg"},
        {".jnlp", "application/x-java-jnlp-file"},
        {".jpb", "application/octet-stream"},
        {".jpe", "image/jpeg"},
        {".jpeg", "image/jpeg"},
        {".jpg", "image/jpeg"},
        {".js", "application/x-javascript"},
        {".json", "application/json"},
        {".jsx", "text/jscript"},
        {".jsxbin", "text/plain"},
        {".latex", "application/x-latex"},
        {".library-ms", "application/windows-library+xml"},
        {".lit", "application/x-ms-reader"},
        {".loadtest", "application/xml"},
        {".lpk", "application/octet-stream"},
        {".lsf", "video/x-la-asf"},
        {".lst", "text/plain"},
        {".lsx", "video/x-la-asf"},
        {".lzh", "application/octet-stream"},
        {".m13", "application/x-msmediaview"},
        {".m14", "application/x-msmediaview"},
        {".m1v", "video/mpeg"},
        {".m2t", "video/vnd.dlna.mpeg-tts"},
        {".m2ts", "video/vnd.dlna.mpeg-tts"},
        {".m2v", "video/mpeg"},
        {".m3u", "audio/x-mpegurl"},
        {".m3u8", "audio/x-mpegurl"},
        {".m4a", "audio/m4a"},
        {".m4b", "audio/m4b"},
        {".m4p", "audio/m4p"},
        {".m4r", "audio/x-m4r"},
        {".m4v", "video/x-m4v"},
        {".mac", "image/x-macpaint"},
        {".mak", "text/plain"},
        {".man", "application/x-troff-man"},
        {".manifest", "application/x-ms-manifest"},
        {".map", "text/plain"},
        {".master", "application/xml"},
        {".mda", "application/msaccess"},
        {".mdb", "application/x-msaccess"},
        {".mde", "application/msaccess"},
        {".mdp", "application/octet-stream"},
        {".me", "application/x-troff-me"},
        {".mfp", "application/x-shockwave-flash"},
        {".mht", "message/rfc822"},
        {".mhtml", "message/rfc822"},
        {".mid", "audio/mid"},
        {".midi", "audio/mid"},
        {".mix", "application/octet-stream"},
        {".mk", "text/plain"},
        {".mmf", "application/x-smaf"},
        {".mno", "text/xml"},
        {".mny", "application/x-msmoney"},
        {".mod", "video/mpeg"},
        {".mov", "video/quicktime"},
        {".movie", "video/x-sgi-movie"},
        {".mp2", "video/mpeg"},
        {".mp2v", "video/mpeg"},
        {".mp3", "audio/mpeg"},
        {".mp4", "video/mp4"},
        {".mp4v", "video/mp4"},
        {".mpa", "video/mpeg"},
        {".mpe", "video/mpeg"},
        {".mpeg", "video/mpeg"},
        {".mpf", "application/vnd.ms-mediapackage"},
        {".mpg", "video/mpeg"},
        {".mpp", "application/vnd.ms-project"},
        {".mpv2", "video/mpeg"},
        {".mqv", "video/quicktime"},
        {".ms", "application/x-troff-ms"},
        {".msi", "application/octet-stream"},
        {".mso", "application/octet-stream"},
        {".mts", "video/vnd.dlna.mpeg-tts"},
        {".mtx", "application/xml"},
        {".mvb", "application/x-msmediaview"},
        {".mvc", "application/x-miva-compiled"},
        {".mxp", "application/x-mmxp"},
        {".nc", "application/x-netcdf"},
        {".nsc", "video/x-ms-asf"},
        {".nws", "message/rfc822"},
        {".ocx", "application/octet-stream"},
        {".oda", "application/oda"},
        {".odc", "text/x-ms-odc"},
        {".odh", "text/plain"},
        {".odl", "text/plain"},
        {".odp", "application/vnd.oasis.opendocument.presentation"},
        {".ods", "application/oleobject"},
        {".odt", "application/vnd.oasis.opendocument.text"},
        {".one", "application/onenote"},
        {".onea", "application/onenote"},
        {".onepkg", "application/onenote"},
        {".onetmp", "application/onenote"},
        {".onetoc", "application/onenote"},
        {".onetoc2", "application/onenote"},
        {".orderedtest", "application/xml"},
        {".osdx", "application/opensearchdescription+xml"},
        {".p10", "application/pkcs10"},
        {".p12", "application/x-pkcs12"},
        {".p7b", "application/x-pkcs7-certificates"},
        {".p7c", "application/pkcs7-mime"},
        {".p7m", "application/pkcs7-mime"},
        {".p7r", "application/x-pkcs7-certreqresp"},
        {".p7s", "application/pkcs7-signature"},
        {".pbm", "image/x-portable-bitmap"},
        {".pcast", "application/x-podcast"},
        {".pct", "image/pict"},
        {".pcx", "application/octet-stream"},
        {".pcz", "application/octet-stream"},
        {".pdf", "application/pdf"},
        {".pfb", "application/octet-stream"},
        {".pfm", "application/octet-stream"},
        {".pfx", "application/x-pkcs12"},
        {".pgm", "image/x-portable-graymap"},
        {".pic", "image/pict"},
        {".pict", "image/pict"},
        {".pkgdef", "text/plain"},
        {".pkgundef", "text/plain"},
        {".pko", "application/vnd.ms-pki.pko"},
        {".pls", "audio/scpls"},
        {".pma", "application/x-perfmon"},
        {".pmc", "application/x-perfmon"},
        {".pml", "application/x-perfmon"},
        {".pmr", "application/x-perfmon"},
        {".pmw", "application/x-perfmon"},
        {".png", "image/png"},
        {".pnm", "image/x-portable-anymap"},
        {".pnt", "image/x-macpaint"},
        {".pntg", "image/x-macpaint"},
        {".pnz", "image/png"},
        {".pot", "application/vnd.ms-powerpoint"},
        {".potm", "application/vnd.ms-powerpoint.template.macroEnabled.12"},
        {".potx", "application/vnd.openxmlformats-officedocument.presentationml.template"},
        {".ppa", "application/vnd.ms-powerpoint"},
        {".ppam", "application/vnd.ms-powerpoint.addin.macroEnabled.12"},
        {".ppm", "image/x-portable-pixmap"},
        {".pps", "application/vnd.ms-powerpoint"},
        {".ppsm", "application/vnd.ms-powerpoint.slideshow.macroEnabled.12"},
        {".ppsx", "application/vnd.openxmlformats-officedocument.presentationml.slideshow"},
        {".ppt", "application/vnd.ms-powerpoint"},
        {".pptm", "application/vnd.ms-powerpoint.presentation.macroEnabled.12"},
        {".pptx", "application/vnd.openxmlformats-officedocument.presentationml.presentation"},
        {".prf", "application/pics-rules"},
        {".prm", "application/octet-stream"},
        {".prx", "application/octet-stream"},
        {".ps", "application/postscript"},
        {".psc1", "application/PowerShell"},
        {".psd", "application/octet-stream"},
        {".psess", "application/xml"},
        {".psm", "application/octet-stream"},
        {".psp", "application/octet-stream"},
        {".pub", "application/x-mspublisher"},
        {".pwz", "application/vnd.ms-powerpoint"},
        {".qht", "text/x-html-insertion"},
        {".qhtm", "text/x-html-insertion"},
        {".qt", "video/quicktime"},
        {".qti", "image/x-quicktime"},
        {".qtif", "image/x-quicktime"},
        {".qtl", "application/x-quicktimeplayer"},
        {".qxd", "application/octet-stream"},
        {".ra", "audio/x-pn-realaudio"},
        {".ram", "audio/x-pn-realaudio"},
        {".rar", "application/octet-stream"},
        {".ras", "image/x-cmu-raster"},
        {".rat", "application/rat-file"},
        {".rc", "text/plain"},
        {".rc2", "text/plain"},
        {".rct", "text/plain"},
        {".rdlc", "application/xml"},
        {".resx", "application/xml"},
        {".rf", "image/vnd.rn-realflash"},
        {".rgb", "image/x-rgb"},
        {".rgs", "text/plain"},
        {".rm", "application/vnd.rn-realmedia"},
        {".rmi", "audio/mid"},
        {".rmp", "application/vnd.rn-rn_music_package"},
        {".roff", "application/x-troff"},
        {".rpm", "audio/x-pn-realaudio-plugin"},
        {".rqy", "text/x-ms-rqy"},
        {".rtf", "application/rtf"},
        {".rtx", "text/richtext"},
        {".ruleset", "application/xml"},
        {".s", "text/plain"},
        {".safariextz", "application/x-safari-safariextz"},
        {".scd", "application/x-msschedule"},
        {".sct", "text/scriptlet"},
        {".sd2", "audio/x-sd2"},
        {".sdp", "application/sdp"},
        {".sea", "application/octet-stream"},
        {".searchConnector-ms", "application/windows-search-connector+xml"},
        {".setpay", "application/set-payment-initiation"},
        {".setreg", "application/set-registration-initiation"},
        {".settings", "application/xml"},
        {".sgimb", "application/x-sgimb"},
        {".sgml", "text/sgml"},
        {".sh", "application/x-sh"},
        {".shar", "application/x-shar"},
        {".shtml", "text/html"},
        {".sit", "application/x-stuffit"},
        {".sitemap", "application/xml"},
        {".skin", "application/xml"},
        {".sldm", "application/vnd.ms-powerpoint.slide.macroEnabled.12"},
        {".sldx", "application/vnd.openxmlformats-officedocument.presentationml.slide"},
        {".slk", "application/vnd.ms-excel"},
        {".sln", "text/plain"},
        {".slupkg-ms", "application/x-ms-license"},
        {".smd", "audio/x-smd"},
        {".smi", "application/octet-stream"},
        {".smx", "audio/x-smd"},
        {".smz", "audio/x-smd"},
        {".snd", "audio/basic"},
        {".snippet", "application/xml"},
        {".snp", "application/octet-stream"},
        {".sol", "text/plain"},
        {".sor", "text/plain"},
        {".spc", "application/x-pkcs7-certificates"},
        {".spl", "application/futuresplash"},
        {".src", "application/x-wais-source"},
        {".srf", "text/plain"},
        {".SSISDeploymentManifest", "text/xml"},
        {".ssm", "application/streamingmedia"},
        {".sst", "application/vnd.ms-pki.certstore"},
        {".stl", "application/vnd.ms-pki.stl"},
        {".sv4cpio", "application/x-sv4cpio"},
        {".sv4crc", "application/x-sv4crc"},
        {".svc", "application/xml"},
        {".swf", "application/x-shockwave-flash"},
        {".t", "application/x-troff"},
        {".tar", "application/x-tar"},
        {".tcl", "application/x-tcl"},
        {".testrunconfig", "application/xml"},
        {".testsettings", "application/xml"},
        {".tex", "application/x-tex"},
        {".texi", "application/x-texinfo"},
        {".texinfo", "application/x-texinfo"},
        {".tgz", "application/x-compressed"},
        {".thmx", "application/vnd.ms-officetheme"},
        {".thn", "application/octet-stream"},
        {".tif", "image/tiff"},
        {".tiff", "image/tiff"},
        {".tlh", "text/plain"},
        {".tli", "text/plain"},
        {".toc", "application/octet-stream"},
        {".tr", "application/x-troff"},
        {".trm", "application/x-msterminal"},
        {".trx", "application/xml"},
        {".ts", "video/vnd.dlna.mpeg-tts"},
        {".tsv", "text/tab-separated-values"},
        {".ttf", "application/octet-stream"},
        {".tts", "video/vnd.dlna.mpeg-tts"},
        {".txt", "text/plain"},
        {".u32", "application/octet-stream"},
        {".uls", "text/iuls"},
        {".user", "text/plain"},
        {".ustar", "application/x-ustar"},
        {".vb", "text/plain"},
        {".vbdproj", "text/plain"},
        {".vbk", "video/mpeg"},
        {".vbproj", "text/plain"},
        {".vbs", "text/vbscript"},
        {".vcf", "text/x-vcard"},
        {".vcproj", "Application/xml"},
        {".vcs", "text/plain"},
        {".vcxproj", "Application/xml"},
        {".vddproj", "text/plain"},
        {".vdp", "text/plain"},
        {".vdproj", "text/plain"},
        {".vdx", "application/vnd.ms-visio.viewer"},
        {".vml", "text/xml"},
        {".vscontent", "application/xml"},
        {".vsct", "text/xml"},
        {".vsd", "application/vnd.visio"},
        {".vsi", "application/ms-vsi"},
        {".vsix", "application/vsix"},
        {".vsixlangpack", "text/xml"},
        {".vsixmanifest", "text/xml"},
        {".vsmdi", "application/xml"},
        {".vspscc", "text/plain"},
        {".vss", "application/vnd.visio"},
        {".vsscc", "text/plain"},
        {".vssettings", "text/xml"},
        {".vssscc", "text/plain"},
        {".vst", "application/vnd.visio"},
        {".vstemplate", "text/xml"},
        {".vsto", "application/x-ms-vsto"},
        {".vsw", "application/vnd.visio"},
        {".vsx", "application/vnd.visio"},
        {".vtx", "application/vnd.visio"},
        {".wav", "audio/wav"},
        {".wave", "audio/wav"},
        {".wax", "audio/x-ms-wax"},
        {".wbk", "application/msword"},
        {".wbmp", "image/vnd.wap.wbmp"},
        {".wcm", "application/vnd.ms-works"},
        {".wdb", "application/vnd.ms-works"},
        {".wdp", "image/vnd.ms-photo"},
        {".webarchive", "application/x-safari-webarchive"},
        {".webtest", "application/xml"},
        {".wiq", "application/xml"},
        {".wiz", "application/msword"},
        {".wks", "application/vnd.ms-works"},
        {".WLMP", "application/wlmoviemaker"},
        {".wlpginstall", "application/x-wlpg-detect"},
        {".wlpginstall3", "application/x-wlpg3-detect"},
        {".wm", "video/x-ms-wm"},
        {".wma", "audio/x-ms-wma"},
        {".wmd", "application/x-ms-wmd"},
        {".wmf", "application/x-msmetafile"},
        {".wml", "text/vnd.wap.wml"},
        {".wmlc", "application/vnd.wap.wmlc"},
        {".wmls", "text/vnd.wap.wmlscript"},
        {".wmlsc", "application/vnd.wap.wmlscriptc"},
        {".wmp", "video/x-ms-wmp"},
        {".wmv", "video/x-ms-wmv"},
        {".wmx", "video/x-ms-wmx"},
        {".wmz", "application/x-ms-wmz"},
        {".wpl", "application/vnd.ms-wpl"},
        {".wps", "application/vnd.ms-works"},
        {".wri", "application/x-mswrite"},
        {".wrl", "x-world/x-vrml"},
        {".wrz", "x-world/x-vrml"},
        {".wsc", "text/scriptlet"},
        {".wsdl", "text/xml"},
        {".wvx", "video/x-ms-wvx"},
        {".x", "application/directx"},
        {".xaf", "x-world/x-vrml"},
        {".xaml", "application/xaml+xml"},
        {".xap", "application/x-silverlight-app"},
        {".xbap", "application/x-ms-xbap"},
        {".xbm", "image/x-xbitmap"},
        {".xdr", "text/plain"},
        {".xht", "application/xhtml+xml"},
        {".xhtml", "application/xhtml+xml"},
        {".xla", "application/vnd.ms-excel"},
        {".xlam", "application/vnd.ms-excel.addin.macroEnabled.12"},
        {".xlc", "application/vnd.ms-excel"},
        {".xld", "application/vnd.ms-excel"},
        {".xlk", "application/vnd.ms-excel"},
        {".xll", "application/vnd.ms-excel"},
        {".xlm", "application/vnd.ms-excel"},
        {".xls", "application/vnd.ms-excel"},
        {".xlsb", "application/vnd.ms-excel.sheet.binary.macroEnabled.12"},
        {".xlsm", "application/vnd.ms-excel.sheet.macroEnabled.12"},
        {".xlsx", "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet"},
        {".xlt", "application/vnd.ms-excel"},
        {".xltm", "application/vnd.ms-excel.template.macroEnabled.12"},
        {".xltx", "application/vnd.openxmlformats-officedocument.spreadsheetml.template"},
        {".xlw", "application/vnd.ms-excel"},
        {".xml", "text/xml"},
        {".xmta", "application/xml"},
        {".xof", "x-world/x-vrml"},
        {".XOML", "text/plain"},
        {".xpm", "image/x-xpixmap"},
        {".xps", "application/vnd.ms-xpsdocument"},
        {".xrm-ms", "text/xml"},
        {".xsc", "application/xml"},
        {".xsd", "text/xml"},
        {".xsf", "text/xml"},
        {".xsl", "text/xml"},
        {".xslt", "text/xml"},
        {".xsn", "application/octet-stream"},
        {".xss", "application/xml"},
        {".xtp", "application/octet-stream"},
        {".xwd", "image/x-xwindowdump"},
        {".z", "application/x-compress"},
        {".zip", "application/x-zip-compressed"},
        #endregion
        
        };

public static string GetMimeType(string extension)
{
    if (extension == null)
    {
        throw new ArgumentNullException("extension");
    }

    if (!extension.StartsWith("."))
    {
        extension = "." + extension;
    }
    
    string mime;
    
    return _mappings.TryGetValue(extension, out mime) ? mime : "application/octet-stream";
}

You can use this helper function:

private string GetMimeType (string fileName)
{
    string mimeType = "application/unknown";
    string ext = System.IO.Path.GetExtension(fileName).ToLower();
    Microsoft.Win32.RegistryKey regKey = Microsoft.Win32.Registry.ClassesRoot.OpenSubKey(ext);
    if (regKey != null && regKey.GetValue("Content Type") != null)
    mimeType = regKey.GetValue("Content Type").ToString();
    return mimeType;
}

Just to make Shimmy's answer more clear:

var mimeType = MimeMapping.GetMimeMapping(fileName);

System.Web.dll v4.5

// Summary:
//     Returns the MIME mapping for the specified file name.
//
// Parameters:
//   fileName:
//     The file name that is used to determine the MIME type.
public static string GetMimeMapping(string fileName);

I like the work that Samuel Neff did, but not the idea and overhead of creating a dictionary every time.

I restructured things as a switch case. Yes you can't iterate over it but in my case I only ever use it to quickly look up a value. Especially because it is done in a web service, the last thing I want is a bunch of overhead as the application prepares its structures. The compiler will turn this into a hashed lookup and so it will be very fast.

public static string GetMimeType(string extension)
{
  if (extension == null)
    throw new ArgumentNullException("extension");

  if (extension.StartsWith("."))
    extension = extension.Substring(1);


  switch (extension.ToLower())
{
    #region Big freaking list of mime types
    case "323": return "text/h323";
    case "3g2": return "video/3gpp2";
    case "3gp": return "video/3gpp";
    case "3gp2": return "video/3gpp2";
    case "3gpp": return "video/3gpp";
    case "7z": return "application/x-7z-compressed";
    case "aa": return "audio/audible";
    case "aac": return "audio/aac";
    case "aaf": return "application/octet-stream";
    case "aax": return "audio/vnd.audible.aax";
    case "ac3": return "audio/ac3";
    case "aca": return "application/octet-stream";
    case "accda": return "application/msaccess.addin";
    case "accdb": return "application/msaccess";
    case "accdc": return "application/msaccess.cab";
    case "accde": return "application/msaccess";
    case "accdr": return "application/msaccess.runtime";
    case "accdt": return "application/msaccess";
    case "accdw": return "application/msaccess.webapplication";
    case "accft": return "application/msaccess.ftemplate";
    case "acx": return "application/internet-property-stream";
    case "addin": return "text/xml";
    case "ade": return "application/msaccess";
    case "adobebridge": return "application/x-bridge-url";
    case "adp": return "application/msaccess";
    case "adt": return "audio/vnd.dlna.adts";
    case "adts": return "audio/aac";
    case "afm": return "application/octet-stream";
    case "ai": return "application/postscript";
    case "aif": return "audio/x-aiff";
    case "aifc": return "audio/aiff";
    case "aiff": return "audio/aiff";
    case "air": return "application/vnd.adobe.air-application-installer-package+zip";
    case "amc": return "application/x-mpeg";
    case "application": return "application/x-ms-application";
    case "art": return "image/x-jg";
    case "asa": return "application/xml";
    case "asax": return "application/xml";
    case "ascx": return "application/xml";
    case "asd": return "application/octet-stream";
    case "asf": return "video/x-ms-asf";
    case "ashx": return "application/xml";
    case "asi": return "application/octet-stream";
    case "asm": return "text/plain";
    case "asmx": return "application/xml";
    case "aspx": return "application/xml";
    case "asr": return "video/x-ms-asf";
    case "asx": return "video/x-ms-asf";
    case "atom": return "application/atom+xml";
    case "au": return "audio/basic";
    case "avi": return "video/x-msvideo";
    case "axs": return "application/olescript";
    case "bas": return "text/plain";
    case "bcpio": return "application/x-bcpio";
    case "bin": return "application/octet-stream";
    case "bmp": return "image/bmp";
    case "c": return "text/plain";
    case "cab": return "application/octet-stream";
    case "caf": return "audio/x-caf";
    case "calx": return "application/vnd.ms-office.calx";
    case "cat": return "application/vnd.ms-pki.seccat";
    case "cc": return "text/plain";
    case "cd": return "text/plain";
    case "cdda": return "audio/aiff";
    case "cdf": return "application/x-cdf";
    case "cer": return "application/x-x509-ca-cert";
    case "chm": return "application/octet-stream";
    case "class": return "application/x-java-applet";
    case "clp": return "application/x-msclip";
    case "cmx": return "image/x-cmx";
    case "cnf": return "text/plain";
    case "cod": return "image/cis-cod";
    case "config": return "application/xml";
    case "contact": return "text/x-ms-contact";
    case "coverage": return "application/xml";
    case "cpio": return "application/x-cpio";
    case "cpp": return "text/plain";
    case "crd": return "application/x-mscardfile";
    case "crl": return "application/pkix-crl";
    case "crt": return "application/x-x509-ca-cert";
    case "cs": return "text/plain";
    case "csdproj": return "text/plain";
    case "csh": return "application/x-csh";
    case "csproj": return "text/plain";
    case "css": return "text/css";
    case "csv": return "text/csv";
    case "cur": return "application/octet-stream";
    case "cxx": return "text/plain";
    case "dat": return "application/octet-stream";
    case "datasource": return "application/xml";
    case "dbproj": return "text/plain";
    case "dcr": return "application/x-director";
    case "def": return "text/plain";
    case "deploy": return "application/octet-stream";
    case "der": return "application/x-x509-ca-cert";
    case "dgml": return "application/xml";
    case "dib": return "image/bmp";
    case "dif": return "video/x-dv";
    case "dir": return "application/x-director";
    case "disco": return "text/xml";
    case "dll": return "application/x-msdownload";
    case "dll.config": return "text/xml";
    case "dlm": return "text/dlm";
    case "doc": return "application/msword";
    case "docm": return "application/vnd.ms-word.document.macroenabled.12";
    case "docx": return "application/vnd.openxmlformats-officedocument.wordprocessingml.document";
    case "dot": return "application/msword";
    case "dotm": return "application/vnd.ms-word.template.macroenabled.12";
    case "dotx": return "application/vnd.openxmlformats-officedocument.wordprocessingml.template";
    case "dsp": return "application/octet-stream";
    case "dsw": return "text/plain";
    case "dtd": return "text/xml";
    case "dtsconfig": return "text/xml";
    case "dv": return "video/x-dv";
    case "dvi": return "application/x-dvi";
    case "dwf": return "drawing/x-dwf";
    case "dwp": return "application/octet-stream";
    case "dxr": return "application/x-director";
    case "eml": return "message/rfc822";
    case "emz": return "application/octet-stream";
    case "eot": return "application/octet-stream";
    case "eps": return "application/postscript";
    case "etl": return "application/etl";
    case "etx": return "text/x-setext";
    case "evy": return "application/envoy";
    case "exe": return "application/octet-stream";
    case "exe.config": return "text/xml";
    case "fdf": return "application/vnd.fdf";
    case "fif": return "application/fractals";
    case "filters": return "application/xml";
    case "fla": return "application/octet-stream";
    case "flr": return "x-world/x-vrml";
    case "flv": return "video/x-flv";
    case "fsscript": return "application/fsharp-script";
    case "fsx": return "application/fsharp-script";
    case "generictest": return "application/xml";
    case "gif": return "image/gif";
    case "group": return "text/x-ms-group";
    case "gsm": return "audio/x-gsm";
    case "gtar": return "application/x-gtar";
    case "gz": return "application/x-gzip";
    case "h": return "text/plain";
    case "hdf": return "application/x-hdf";
    case "hdml": return "text/x-hdml";
    case "hhc": return "application/x-oleobject";
    case "hhk": return "application/octet-stream";
    case "hhp": return "application/octet-stream";
    case "hlp": return "application/winhlp";
    case "hpp": return "text/plain";
    case "hqx": return "application/mac-binhex40";
    case "hta": return "application/hta";
    case "htc": return "text/x-component";
    case "htm": return "text/html";
    case "html": return "text/html";
    case "htt": return "text/webviewhtml";
    case "hxa": return "application/xml";
    case "hxc": return "application/xml";
    case "hxd": return "application/octet-stream";
    case "hxe": return "application/xml";
    case "hxf": return "application/xml";
    case "hxh": return "application/octet-stream";
    case "hxi": return "application/octet-stream";
    case "hxk": return "application/xml";
    case "hxq": return "application/octet-stream";
    case "hxr": return "application/octet-stream";
    case "hxs": return "application/octet-stream";
    case "hxt": return "text/html";
    case "hxv": return "application/xml";
    case "hxw": return "application/octet-stream";
    case "hxx": return "text/plain";
    case "i": return "text/plain";
    case "ico": return "image/x-icon";
    case "ics": return "application/octet-stream";
    case "idl": return "text/plain";
    case "ief": return "image/ief";
    case "iii": return "application/x-iphone";
    case "inc": return "text/plain";
    case "inf": return "application/octet-stream";
    case "inl": return "text/plain";
    case "ins": return "application/x-internet-signup";
    case "ipa": return "application/x-itunes-ipa";
    case "ipg": return "application/x-itunes-ipg";
    case "ipproj": return "text/plain";
    case "ipsw": return "application/x-itunes-ipsw";
    case "iqy": return "text/x-ms-iqy";
    case "isp": return "application/x-internet-signup";
    case "ite": return "application/x-itunes-ite";
    case "itlp": return "application/x-itunes-itlp";
    case "itms": return "application/x-itunes-itms";
    case "itpc": return "application/x-itunes-itpc";
    case "ivf": return "video/x-ivf";
    case "jar": return "application/java-archive";
    case "java": return "application/octet-stream";
    case "jck": return "application/liquidmotion";
    case "jcz": return "application/liquidmotion";
    case "jfif": return "image/pjpeg";
    case "jnlp": return "application/x-java-jnlp-file";
    case "jpb": return "application/octet-stream";
    case "jpe": return "image/jpeg";
    case "jpeg": return "image/jpeg";
    case "jpg": return "image/jpeg";
    case "js": return "application/x-javascript";
    case "jsx": return "text/jscript";
    case "jsxbin": return "text/plain";
    case "latex": return "application/x-latex";
    case "library-ms": return "application/windows-library+xml";
    case "lit": return "application/x-ms-reader";
    case "loadtest": return "application/xml";
    case "lpk": return "application/octet-stream";
    case "lsf": return "video/x-la-asf";
    case "lst": return "text/plain";
    case "lsx": return "video/x-la-asf";
    case "lzh": return "application/octet-stream";
    case "m13": return "application/x-msmediaview";
    case "m14": return "application/x-msmediaview";
    case "m1v": return "video/mpeg";
    case "m2t": return "video/vnd.dlna.mpeg-tts";
    case "m2ts": return "video/vnd.dlna.mpeg-tts";
    case "m2v": return "video/mpeg";
    case "m3u": return "audio/x-mpegurl";
    case "m3u8": return "audio/x-mpegurl";
    case "m4a": return "audio/m4a";
    case "m4b": return "audio/m4b";
    case "m4p": return "audio/m4p";
    case "m4r": return "audio/x-m4r";
    case "m4v": return "video/x-m4v";
    case "mac": return "image/x-macpaint";
    case "mak": return "text/plain";
    case "man": return "application/x-troff-man";
    case "manifest": return "application/x-ms-manifest";
    case "map": return "text/plain";
    case "master": return "application/xml";
    case "mda": return "application/msaccess";
    case "mdb": return "application/x-msaccess";
    case "mde": return "application/msaccess";
    case "mdp": return "application/octet-stream";
    case "me": return "application/x-troff-me";
    case "mfp": return "application/x-shockwave-flash";
    case "mht": return "message/rfc822";
    case "mhtml": return "message/rfc822";
    case "mid": return "audio/mid";
    case "midi": return "audio/mid";
    case "mix": return "application/octet-stream";
    case "mk": return "text/plain";
    case "mmf": return "application/x-smaf";
    case "mno": return "text/xml";
    case "mny": return "application/x-msmoney";
    case "mod": return "video/mpeg";
    case "mov": return "video/quicktime";
    case "movie": return "video/x-sgi-movie";
    case "mp2": return "video/mpeg";
    case "mp2v": return "video/mpeg";
    case "mp3": return "audio/mpeg";
    case "mp4": return "video/mp4";
    case "mp4v": return "video/mp4";
    case "mpa": return "video/mpeg";
    case "mpe": return "video/mpeg";
    case "mpeg": return "video/mpeg";
    case "mpf": return "application/vnd.ms-mediapackage";
    case "mpg": return "video/mpeg";
    case "mpp": return "application/vnd.ms-project";
    case "mpv2": return "video/mpeg";
    case "mqv": return "video/quicktime";
    case "ms": return "application/x-troff-ms";
    case "msi": return "application/octet-stream";
    case "mso": return "application/octet-stream";
    case "mts": return "video/vnd.dlna.mpeg-tts";
    case "mtx": return "application/xml";
    case "mvb": return "application/x-msmediaview";
    case "mvc": return "application/x-miva-compiled";
    case "mxp": return "application/x-mmxp";
    case "nc": return "application/x-netcdf";
    case "nsc": return "video/x-ms-asf";
    case "nws": return "message/rfc822";
    case "ocx": return "application/octet-stream";
    case "oda": return "application/oda";
    case "odc": return "text/x-ms-odc";
    case "odh": return "text/plain";
    case "odl": return "text/plain";
    case "odp": return "application/vnd.oasis.opendocument.presentation";
    case "ods": return "application/oleobject";
    case "odt": return "application/vnd.oasis.opendocument.text";
    case "one": return "application/onenote";
    case "onea": return "application/onenote";
    case "onepkg": return "application/onenote";
    case "onetmp": return "application/onenote";
    case "onetoc": return "application/onenote";
    case "onetoc2": return "application/onenote";
    case "orderedtest": return "application/xml";
    case "osdx": return "application/opensearchdescription+xml";
    case "p10": return "application/pkcs10";
    case "p12": return "application/x-pkcs12";
    case "p7b": return "application/x-pkcs7-certificates";
    case "p7c": return "application/pkcs7-mime";
    case "p7m": return "application/pkcs7-mime";
    case "p7r": return "application/x-pkcs7-certreqresp";
    case "p7s": return "application/pkcs7-signature";
    case "pbm": return "image/x-portable-bitmap";
    case "pcast": return "application/x-podcast";
    case "pct": return "image/pict";
    case "pcx": return "application/octet-stream";
    case "pcz": return "application/octet-stream";
    case "pdf": return "application/pdf";
    case "pfb": return "application/octet-stream";
    case "pfm": return "application/octet-stream";
    case "pfx": return "application/x-pkcs12";
    case "pgm": return "image/x-portable-graymap";
    case "pic": return "image/pict";
    case "pict": return "image/pict";
    case "pkgdef": return "text/plain";
    case "pkgundef": return "text/plain";
    case "pko": return "application/vnd.ms-pki.pko";
    case "pls": return "audio/scpls";
    case "pma": return "application/x-perfmon";
    case "pmc": return "application/x-perfmon";
    case "pml": return "application/x-perfmon";
    case "pmr": return "application/x-perfmon";
    case "pmw": return "application/x-perfmon";
    case "png": return "image/png";
    case "pnm": return "image/x-portable-anymap";
    case "pnt": return "image/x-macpaint";
    case "pntg": return "image/x-macpaint";
    case "pnz": return "image/png";
    case "pot": return "application/vnd.ms-powerpoint";
    case "potm": return "application/vnd.ms-powerpoint.template.macroenabled.12";
    case "potx": return "application/vnd.openxmlformats-officedocument.presentationml.template";
    case "ppa": return "application/vnd.ms-powerpoint";
    case "ppam": return "application/vnd.ms-powerpoint.addin.macroenabled.12";
    case "ppm": return "image/x-portable-pixmap";
    case "pps": return "application/vnd.ms-powerpoint";
    case "ppsm": return "application/vnd.ms-powerpoint.slideshow.macroenabled.12";
    case "ppsx": return "application/vnd.openxmlformats-officedocument.presentationml.slideshow";
    case "ppt": return "application/vnd.ms-powerpoint";
    case "pptm": return "application/vnd.ms-powerpoint.presentation.macroenabled.12";
    case "pptx": return "application/vnd.openxmlformats-officedocument.presentationml.presentation";
    case "prf": return "application/pics-rules";
    case "prm": return "application/octet-stream";
    case "prx": return "application/octet-stream";
    case "ps": return "application/postscript";
    case "psc1": return "application/powershell";
    case "psd": return "application/octet-stream";
    case "psess": return "application/xml";
    case "psm": return "application/octet-stream";
    case "psp": return "application/octet-stream";
    case "pub": return "application/x-mspublisher";
    case "pwz": return "application/vnd.ms-powerpoint";
    case "qht": return "text/x-html-insertion";
    case "qhtm": return "text/x-html-insertion";
    case "qt": return "video/quicktime";
    case "qti": return "image/x-quicktime";
    case "qtif": return "image/x-quicktime";
    case "qtl": return "application/x-quicktimeplayer";
    case "qxd": return "application/octet-stream";
    case "ra": return "audio/x-pn-realaudio";
    case "ram": return "audio/x-pn-realaudio";
    case "rar": return "application/octet-stream";
    case "ras": return "image/x-cmu-raster";
    case "rat": return "application/rat-file";
    case "rc": return "text/plain";
    case "rc2": return "text/plain";
    case "rct": return "text/plain";
    case "rdlc": return "application/xml";
    case "resx": return "application/xml";
    case "rf": return "image/vnd.rn-realflash";
    case "rgb": return "image/x-rgb";
    case "rgs": return "text/plain";
    case "rm": return "application/vnd.rn-realmedia";
    case "rmi": return "audio/mid";
    case "rmp": return "application/vnd.rn-rn_music_package";
    case "roff": return "application/x-troff";
    case "rpm": return "audio/x-pn-realaudio-plugin";
    case "rqy": return "text/x-ms-rqy";
    case "rtf": return "application/rtf";
    case "rtx": return "text/richtext";
    case "ruleset": return "application/xml";
    case "s": return "text/plain";
    case "safariextz": return "application/x-safari-safariextz";
    case "scd": return "application/x-msschedule";
    case "sct": return "text/scriptlet";
    case "sd2": return "audio/x-sd2";
    case "sdp": return "application/sdp";
    case "sea": return "application/octet-stream";
    case "searchconnector-ms": return "application/windows-search-connector+xml";
    case "setpay": return "application/set-payment-initiation";
    case "setreg": return "application/set-registration-initiation";
    case "settings": return "application/xml";
    case "sgimb": return "application/x-sgimb";
    case "sgml": return "text/sgml";
    case "sh": return "application/x-sh";
    case "shar": return "application/x-shar";
    case "shtml": return "text/html";
    case "sit": return "application/x-stuffit";
    case "sitemap": return "application/xml";
    case "skin": return "application/xml";
    case "sldm": return "application/vnd.ms-powerpoint.slide.macroenabled.12";
    case "sldx": return "application/vnd.openxmlformats-officedocument.presentationml.slide";
    case "slk": return "application/vnd.ms-excel";
    case "sln": return "text/plain";
    case "slupkg-ms": return "application/x-ms-license";
    case "smd": return "audio/x-smd";
    case "smi": return "application/octet-stream";
    case "smx": return "audio/x-smd";
    case "smz": return "audio/x-smd";
    case "snd": return "audio/basic";
    case "snippet": return "application/xml";
    case "snp": return "application/octet-stream";
    case "sol": return "text/plain";
    case "sor": return "text/plain";
    case "spc": return "application/x-pkcs7-certificates";
    case "spl": return "application/futuresplash";
    case "src": return "application/x-wais-source";
    case "srf": return "text/plain";
    case "ssisdeploymentmanifest": return "text/xml";
    case "ssm": return "application/streamingmedia";
    case "sst": return "application/vnd.ms-pki.certstore";
    case "stl": return "application/vnd.ms-pki.stl";
    case "sv4cpio": return "application/x-sv4cpio";
    case "sv4crc": return "application/x-sv4crc";
    case "svc": return "application/xml";
    case "swf": return "application/x-shockwave-flash";
    case "t": return "application/x-troff";
    case "tar": return "application/x-tar";
    case "tcl": return "application/x-tcl";
    case "testrunconfig": return "application/xml";
    case "testsettings": return "application/xml";
    case "tex": return "application/x-tex";
    case "texi": return "application/x-texinfo";
    case "texinfo": return "application/x-texinfo";
    case "tgz": return "application/x-compressed";
    case "thmx": return "application/vnd.ms-officetheme";
    case "thn": return "application/octet-stream";
    case "tif": return "image/tiff";
    case "tiff": return "image/tiff";
    case "tlh": return "text/plain";
    case "tli": return "text/plain";
    case "toc": return "application/octet-stream";
    case "tr": return "application/x-troff";
    case "trm": return "application/x-msterminal";
    case "trx": return "application/xml";
    case "ts": return "video/vnd.dlna.mpeg-tts";
    case "tsv": return "text/tab-separated-values";
    case "ttf": return "application/octet-stream";
    case "tts": return "video/vnd.dlna.mpeg-tts";
    case "txt": return "text/plain";
    case "u32": return "application/octet-stream";
    case "uls": return "text/iuls";
    case "user": return "text/plain";
    case "ustar": return "application/x-ustar";
    case "vb": return "text/plain";
    case "vbdproj": return "text/plain";
    case "vbk": return "video/mpeg";
    case "vbproj": return "text/plain";
    case "vbs": return "text/vbscript";
    case "vcf": return "text/x-vcard";
    case "vcproj": return "application/xml";
    case "vcs": return "text/plain";
    case "vcxproj": return "application/xml";
    case "vddproj": return "text/plain";
    case "vdp": return "text/plain";
    case "vdproj": return "text/plain";
    case "vdx": return "application/vnd.ms-visio.viewer";
    case "vml": return "text/xml";
    case "vscontent": return "application/xml";
    case "vsct": return "text/xml";
    case "vsd": return "application/vnd.visio";
    case "vsi": return "application/ms-vsi";
    case "vsix": return "application/vsix";
    case "vsixlangpack": return "text/xml";
    case "vsixmanifest": return "text/xml";
    case "vsmdi": return "application/xml";
    case "vspscc": return "text/plain";
    case "vss": return "application/vnd.visio";
    case "vsscc": return "text/plain";
    case "vssettings": return "text/xml";
    case "vssscc": return "text/plain";
    case "vst": return "application/vnd.visio";
    case "vstemplate": return "text/xml";
    case "vsto": return "application/x-ms-vsto";
    case "vsw": return "application/vnd.visio";
    case "vsx": return "application/vnd.visio";
    case "vtx": return "application/vnd.visio";
    case "wav": return "audio/wav";
    case "wave": return "audio/wav";
    case "wax": return "audio/x-ms-wax";
    case "wbk": return "application/msword";
    case "wbmp": return "image/vnd.wap.wbmp";
    case "wcm": return "application/vnd.ms-works";
    case "wdb": return "application/vnd.ms-works";
    case "wdp": return "image/vnd.ms-photo";
    case "webarchive": return "application/x-safari-webarchive";
    case "webtest": return "application/xml";
    case "wiq": return "application/xml";
    case "wiz": return "application/msword";
    case "wks": return "application/vnd.ms-works";
    case "wlmp": return "application/wlmoviemaker";
    case "wlpginstall": return "application/x-wlpg-detect";
    case "wlpginstall3": return "application/x-wlpg3-detect";
    case "wm": return "video/x-ms-wm";
    case "wma": return "audio/x-ms-wma";
    case "wmd": return "application/x-ms-wmd";
    case "wmf": return "application/x-msmetafile";
    case "wml": return "text/vnd.wap.wml";
    case "wmlc": return "application/vnd.wap.wmlc";
    case "wmls": return "text/vnd.wap.wmlscript";
    case "wmlsc": return "application/vnd.wap.wmlscriptc";
    case "wmp": return "video/x-ms-wmp";
    case "wmv": return "video/x-ms-wmv";
    case "wmx": return "video/x-ms-wmx";
    case "wmz": return "application/x-ms-wmz";
    case "wpl": return "application/vnd.ms-wpl";
    case "wps": return "application/vnd.ms-works";
    case "wri": return "application/x-mswrite";
    case "wrl": return "x-world/x-vrml";
    case "wrz": return "x-world/x-vrml";
    case "wsc": return "text/scriptlet";
    case "wsdl": return "text/xml";
    case "wvx": return "video/x-ms-wvx";
    case "x": return "application/directx";
    case "xaf": return "x-world/x-vrml";
    case "xaml": return "application/xaml+xml";
    case "xap": return "application/x-silverlight-app";
    case "xbap": return "application/x-ms-xbap";
    case "xbm": return "image/x-xbitmap";
    case "xdr": return "text/plain";
    case "xht": return "application/xhtml+xml";
    case "xhtml": return "application/xhtml+xml";
    case "xla": return "application/vnd.ms-excel";
    case "xlam": return "application/vnd.ms-excel.addin.macroenabled.12";
    case "xlc": return "application/vnd.ms-excel";
    case "xld": return "application/vnd.ms-excel";
    case "xlk": return "application/vnd.ms-excel";
    case "xll": return "application/vnd.ms-excel";
    case "xlm": return "application/vnd.ms-excel";
    case "xls": return "application/vnd.ms-excel";
    case "xlsb": return "application/vnd.ms-excel.sheet.binary.macroenabled.12";
    case "xlsm": return "application/vnd.ms-excel.sheet.macroenabled.12";
    case "xlsx": return "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet";
    case "xlt": return "application/vnd.ms-excel";
    case "xltm": return "application/vnd.ms-excel.template.macroenabled.12";
    case "xltx": return "application/vnd.openxmlformats-officedocument.spreadsheetml.template";
    case "xlw": return "application/vnd.ms-excel";
    case "xml": return "text/xml";
    case "xmta": return "application/xml";
    case "xof": return "x-world/x-vrml";
    case "xoml": return "text/plain";
    case "xpm": return "image/x-xpixmap";
    case "xps": return "application/vnd.ms-xpsdocument";
    case "xrm-ms": return "text/xml";
    case "xsc": return "application/xml";
    case "xsd": return "text/xml";
    case "xsf": return "text/xml";
    case "xsl": return "text/xml";
    case "xslt": return "text/xml";
    case "xsn": return "application/octet-stream";
    case "xss": return "application/xml";
    case "xtp": return "application/octet-stream";
    case "xwd": return "image/x-xwindowdump";
    case "z": return "application/x-compress";
    case "zip": return "application/x-zip-compressed";
  #endregion
    default: return "application/octet-stream";
  }
}

You can find that information in the registry. For instance, the MIME type for .pdf file can be found in the key HKEY_CLASSES_ROOT\.pdf, in the value "Content Type" :

string mimeType = Registry.GetValue(@"HKEY_CLASSES_ROOT\.pdf", "Content Type", null) as string;

I've written a program to fetch and convert the Apache mime.types file to a C# Dictionary<string, string> keyed by file extension. It's here.

The actual output is this file (but you might want to grab it and run it again in case the Apache file has been updated since I last ran this).

public static Dictionary<string, string> MimeTypes = new Dictionary<string, string>
{
  { "123", "application/vnd.lotus-1-2-3" },
  { "3dml", "text/vnd.in3d.3dml" },
  { "3g2", "video/3gpp2" },
  { "3gp", "video/3gpp" },
  { "7z", "application/x-7z-compressed" },
  { "aab", "application/x-authorware-bin" },
  { "aac", "audio/x-aac" },
  { "aam", "application/x-authorware-map" },
  { "aas", "application/x-authorware-seg" },
  { "abw", "application/x-abiword" },
  ...