I have a TextBox which needs to be enabled / disabled programmatically. I want to achieve this using a binding to a Boolean. Here is the TextBox XAML:
<TextBox Height="424" HorizontalAlignment="Left" 
                 Margin="179,57,0,0" Name="textBox2" 
                 VerticalAlignment="Top" Width="777"
                 TextWrapping="WrapWithOverflow" 
                 ScrollViewer.CanContentScroll="True" 
                 ScrollViewer.VerticalScrollBarVisibility="Auto" 
                 AcceptsReturn="True" AcceptsTab="True" 
                 Text="{Binding Path=Text, UpdateSourceTrigger=PropertyChanged}"
                 IsEnabled="{Binding Path=TextBoxEnabled}"/>
Notice the Text property is bound as well; it is fully functional, which makes me think it is not a DataContext issue.
However, when I call this code:
private Boolean _textbox_enabled;
public Boolean Textbox_Enabled
{
    get { return _textbox_enabled; }
    set
    {
        OnPropertyChanged("TextBoxEnabled");
    }
}
It does not work. To give further information, the TextBox_Enabled property is changed by this method:
public void DisabledTextBox()
{
     this.Textbox_Enabled = false;
}
..which is called when a key combination is pressed.
Here are your little typos!
    private Boolean _textbox_enabled;
    public Boolean TextboxEnabled // here, underscore typo
    {
        get { return _textbox_enabled; }
        set
        {
            _textbox_enabled = value; // You miss this line, could be ok to do an equality check here to. :)
            OnPropertyChanged("TextboxEnabled"); // 
        }
    }
Another thing for your xaml to update the text to the vm/datacontext
Text="{Binding Path=Text, Mode=TwoWay, UpdateSourceTrigger=PropertyChanged}" IsEnabled="{Binding TextBoxEnabled}"/>
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