A profiler is a tool that monitors the execution of another application. A common language runtime (CLR) profiler is a dynamic link library (DLL) that consists of functions that receive messages from, and send messages to, the CLR by using the profiling API. The profiler DLL is loaded by the CLR at run time.
In Visual Studio 2019, the legacy Performance Explorer and related profiling tools such as the Performance Wizard were folded into the Performance Profiler, which you can open using Debug > Performance Profiler.
If you use the dotTrace extension integrated with Visual Studio, it helps you start profiling the applications from the IDE. You also can view and analyze timeline profiling results right in Visual Studio.
You can use profiling tools to identify which portions of the program are executed most frequently or where most of the time is spent. Profiling tools are typically used after a basic tool, such as the vmstat or iostat commands, shows that a CPU bottleneck is causing a performance problem.
I have used JetBrains dotTrace and Redgate ANTS extensively. They are fairly similar in features and price. They both offer useful performance profiling and quite basic memory profiling.
dotTrace integrates with Resharper, which is really convenient, as you can profile the performance of a unit test with one click from the IDE. However, dotTrace often seems to give spurious results (e.g. saying that a method took several years to run)
I prefer the way that ANTS presents the profiling results. It shows you the source code and to the left of each line tells you how long it took to run. dotTrace just has a tree view.
EQATEC profiler is quite basic and requires you to compile special instrumented versions of your assemblies which can then be run in the EQATEC profiler. It is, however, free.
Overall I prefer ANTS for performance profiling, although if you use Resharper then the integration of dotTrace is a killer feature and means it beats ANTS in usability.
The free Microsoft CLR Profiler (.Net framework 2.0 / .Net Framework 4.0) is all you need for .NET memory profiling.
2011 Update:
The Scitech memory profiler has quite a basic UI but lots of useful information, including some information on unmanaged memory which dotTrace and ANTS lack - you might find it useful if you are doing COM interop, but I have yet to find any profiler that makes COM memory issues easy to diagnose - you usually have to break out windbg.exe
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The ANTS profiler has come on in leaps and bounds in the last few years, and its memory profiler has some truly useful features which now pushed it ahead of dotTrace as a package in my estimation. I'm lucky enough to have licenses for both, but if you are going to buy one .Net profiler for both performance and memory, make it ANTS.
Others have covered performance profiling, but with regards to memory profiling I'm currently evaluating both the Scitech .NET Memory Profiler 3.1 and ANTS Memory Profiler 5.1 (current versions as of September 2009). I tried the JetBrains one a year or two ago and it wasn't as good as ANTS (for memory profiling) so I haven't bothered this time. From reading the web sites it looks like it doesn't have the same memory profiling features as the other two.
Both ANTS and the Scitech memory profiler have features that the other doesn't, so which is best will depend upon your preferences. Generally speaking, the Scitech one provides more detailed information while the ANTS one is really incredible at identifying the leaking object. Overall, I prefer the ANTS one because it is so quick at identifying possible leaks.
Here are the main the pros and cons of each from my experience:
Common Features of ANTS and Scitech .NET Memory Profiler
ANTS
Scitech .NET Memory Profiler
By way of summary, I think ANTS helps you find what's leaking faster while Scitech provides a bit more detail about your overall application memory performance and individual objects once you know what to look at (eg. stack trace on creation). If the stack trace and tracking of undisposed disposable objects was added to ANTS I wouldn't see the need to use anything else.
I recently discovered EQATEC Profiler http://www.eqatec.com/tools/profiler. It works with most .NET versions and on a bunch of platforms. It is easy to use and parts of it is free, even for commercial use.
[Full Disclosure]
While not yet as full-featured as some of the other .NET memory profilers listed here, there is a new entry on the market called JustTrace. It's made by Telerik and it's primary goal is to make tracing/profiling easier and faster to do for all types of apps (web/Silverlight/desktop).
If you've ever found profiling and optimization intimidating or slow with other tools, then JustTrace might be worth a look.
Don't forget nProf - a prefectly good, freeware profiler.
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