I'm a professional Technical Writer, so I use Microsoft Office, Adobe Acrobat, Adobe FrameMaker, Adobe Creative Suite, and RoboHelp on a daily basis, with occasional smatterings of perl, various Linux tools (usually via Cygwin at work), and some VBA macros.
I sometimes play around with web technologies (JavaScript, HTML, XML, CSS, and various APIs).
I also like to dabble in Linux and all that goes with the day-to-day administration of LAMP servers and Linux systems (bash, perl, python, MySQL, etc.)