I have the list of the applications for given file extension (using LSCopyApplicationURLsForURL). I want to change the default file association from code upon selecting one of the applications from the above call. Is there a way to do this?
Here is a snippet of code for a very related task: set yourself as the default application for a given file extension:
#import <ApplicationServices/ApplicationServices.h>
#import "LaunchServicesWrapper.h"
@implementation LaunchServicesWrapper
+ (NSString *) UTIforFileExtension:(NSString *) extension {
    NSString * UTIString = (NSString *)UTTypeCreatePreferredIdentifierForTag(kUTTagClassFilenameExtension, 
                                                                       (CFStringRef)extension, 
                                                                       NULL);
    return [UTIString autorelease];
}
+ (BOOL) setMyselfAsDefaultApplicationForFileExtension:(NSString *) fileExtension {
    OSStatus returnStatus = LSSetDefaultRoleHandlerForContentType (
                                                                   (CFStringRef) [LaunchServicesWrapper UTIforFileExtension:fileExtension],
                                                                   kLSRolesAll,
                                                                   (CFStringRef) [[NSBundle mainBundle] bundleIdentifier]
                                                                   );
    if (returnStatus != 0) {
        NSLog(@"Got an error when setting default application - %d", returnStatus);
        // Please see the documentation or LSInfo.h
        return NO;
    }
    return YES;
}
@end
                        Here’s a slightly modified and ARC-compliant version of Guillaume’s solution:
#import <Foundation/Foundation.h>
@interface LaunchServicesWrapper : NSObject
+ (BOOL)setMyselfAsDefaultApplicationForFileExtension:
  (NSString *)fileExtension;
@end
#import <ApplicationServices/ApplicationServices.h>
#import "LaunchServicesWrapper.h"
@implementation LaunchServicesWrapper
+ (NSString *)UTIforFileExtension:(NSString *)extension
{
  return (NSString *)CFBridgingRelease(
    UTTypeCreatePreferredIdentifierForTag(
      kUTTagClassFilenameExtension, (__bridge CFStringRef)extension,
      NULL
    )
  );
}
+ (BOOL)setMyselfAsDefaultApplicationForFileExtension:
  (NSString *)fileExtension
{
  return LSSetDefaultRoleHandlerForContentType(
    (__bridge CFStringRef) [LaunchServicesWrapper
    UTIforFileExtension:fileExtension], kLSRolesAll,
    (__bridge CFStringRef) [[NSBundle mainBundle]
    bundleIdentifier]
  );
}
@end
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