How do you handle cases when you have, say, a form component, and you need to submit a part of the component's state using button in navigation bar?
const navBtn = (iconName, onPress) => (
  <TouchableOpacity
    onPress={onPress}
    style={styles.iconWrapper}
  >
    <Icon name={iconName} size={cs.iconSize} style={styles.icon} />
  </TouchableOpacity>
)
class ComponentName extends Component {
  static navigationOptions = {
    header: (props) => ({
      tintColor: 'white',
      style: {
        backgroundColor: cs.primaryColor
      },
      left: navBtn('clear', () => props.goBack()),
      right: navBtn('done', () => this.submitForm()), // error: this.submitForm is not a function
    }),
    title: 'Form',
  }
  constructor(props) {
    super(props);
    this.state = {
      formText: ''
    };
  }
  submitForm() {
    this.props.submitFormAction(this.state.formText)
  }
  render() {
    return (
      <View>
        ...form goes here
      </View>
    );
  }
}
                A screen component can have a static property called navigationOptions which is either an object or a function that returns an object that contains various configuration options. The one we use for the header title is title , as demonstrated in the following example.
You can go back to an existing screen in the stack with navigation. navigate('RouteName') , and you can go back to the first screen in the stack with navigation.
Just as a follow-up to @val's excellent answer, here's how I structured my Component so that all the params are set in the componentWillMount. I find this keeps it simpler and is an easy pattern to follow for all other screens. 
static navigationOptions = ({navigation, screenProps}) => {
  const params = navigation.state.params || {};
  return {
    title:       params.title,
    headerLeft:  params.headerLeft,
    headerRight: params.headerRight,
  }
}
_setNavigationParams() {
  let title       = 'Form';
  let headerLeft  = <Button onPress={this._clearForm.bind(this)} />;
  let headerRight = <Button onPress={this._submitForm.bind(this)} />;
  this.props.navigation.setParams({ 
    title,
    headerLeft,
    headerRight, 
  });
}
componentWillMount() {
  this._setNavigationParams();
}
_clearForm() {
  // Clear form code...
}
_submitForm() {
  // Submit form code...
}
                        Send a binded function with setParams, then you will have access to component's state within that function.
Example:
constructor(props) {
    super(props);
    this._handleButtonNext = this._handleButtonNext.bind(this);
    this.state = { selectedIndex: 0 }
}
componentDidMount() {
    this.props.navigation.setParams({
        handleButtonNext: this._handleButtonNext,
    });
}
_handleButtonNext() {
    let action = NavigationActions.setParams({
        params: { selectedImage: images[this.state.selectedIndex] }
    });
    this.props.navigation.dispatch(action);
}
Now you can have a button handler related to component's state.
static navigationOptions = ({ navigation }) => {
    const { state, setParams, navigate } = navigation;
    const params = state.params || {};
    return {
        headerTitleStyle: { alignSelf: 'center' },
        title: 'Select An Icon',
        headerRight: <Button title='Next' onPress={params.handleButtonNext} />
    }
}
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