I'm trying to perform a regex substitution on a bytes variable but I receive the error
  sequence item 0: expected a bytes-like object, str found
Here is a small code example to reproduce the problem with python3:
import re
try:
    test = b'\x1babc\x07123'
    test = re.sub(b"\x1b.*\x07", '', test)
    print(test)
except Exception as e:
    print(e)
                When acting on bytes object, all arguments must be of type byte, including the replacement string. That is:
test = re.sub(b"\x1b.*\x07", b'', test)
                        Your replacement value must be a bytes object too:
re.sub(b"\x1b.*\x07", b'', test)
#                     ^^^
You can't replace matching bytes with a str object, even if that is an empty string object.
Demo:
>>> import re
>>> test = b'\x1babc\x07123'
>>> re.sub(b"\x1b.*\x07", b'', test)
b'123'
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