Assume I have this:
Regex.Replace("aa cc bbbb","aa cc","",RegexOptions.IgnoreCase);
But I also need to ignore white-spaces. So, I found an option IgnorePatternWhitespace, but how can I add several options to one regex.Replace?
Something like:   
Regex.Replace("aa cc bbbb", "aa cc", "", 
    RegexOptions.IgnoreCase + RegexOptions.IgnorePatterWhitespace);
Update:
Thanks for answers but this option does not seem to work: here's a test example:
Regex.Replace("aa cc bbbb", "aacc", "", 
    RegexOptions.IgnoreCase | RegexOptions.IgnorePatterWhitespace);
                Use bitwise OR (|)
Regex.Replace("aa cc bbbb",
                "aa cc",
                "",
                RegexOptions.IgnoreCase | RegexOptions.IgnorePatterWhitespace); 
                        Regex.Replace("aa cc bbbb","aa cc","",RegexOptions.IgnoreCase | RegexOptions.IgnorePatterWhitespace);
Use the | operator.
Edit :
You got it completely wrong. RegexOption.IgnorePatterWhitespace ignores the whitespace in the regex so that you can do : 
string pattern = @"
^                # Beginning of The Line
\d+              # Match one to n number but at least one..
";
You however think that ingoring whitespace makes "aa cc bbbb" into "aaccbbbb" which is thankfully wrong.
According to MSDN:
A bitwise OR combination of RegexOption enumeration values.
So just use OPT_A | OPT_B
You can have as many RegexOptions as you like, just "OR" them with "|".
For example...
RegexOptions.Compiled | RegexOptions.IgnoreCase
                        IgnorePatternWhitespace
Eliminates unescaped white space from the pattern and enables comments marked with #. However, the IgnorePatternWhitespace value does not affect or eliminate white space in character classes.
so:
string result = Regex.Replace("aa cc bbbb","aa|cc","",RegexOptions.IgnoreCase).Trim();
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