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We are currently using a single command line tool to build our product on both Windows and Linux.
Si far its works nicely, allowing us to build out of source and with finer dependencies than what any of our previous build system allowed. This buys us great incremental and parallel build capabilities.
To describe shortly the build process, we get the usual:
.cpp -- cl.exe --> .obj and .pdb
multiple .obj and .pdb -- cl.exe --> single .dll .lib .pdb
multiple .obj and .pdb -- cl.exe --> single .exe .pdb
The msvc C/C++ compiler supports it adequately.
Recently the need to build a few static libraries emerged. From what we gathered, the process to build a static library is:
multiple .cpp -- cl.exe --> multiple .obj and a single .pdb
multiple .obj -- lib.exe --> a single .lib
The single .pdb means that cl.exe should only be executed once for all the .cpp sources. This single execution means that we can't parallelize the build for this static library. This is really unfortunate.
We investigated a bit further and according to the documentation (and the available command line options):
cl.exe does not know how to build static librarieslib.exe does not know how to build .pdb filesDoes anybody know a way to merge multiple PDB files ? Are we doomed to have slow builds for static libraries ? How do tools like Incredibuild work around this issue ?
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next you wanna merge both in one pdb so go through file option select export pdb option molecule as well as click on pdb option and check tick top3 option at end save in pdb file. Use ChimeraX . Open the receptor file and drag the ligand pdbqt file directly to the window. Then select all and save as PDB.
Popular Answers (1) Manually, first use pymol to move two structures close to each other (the distance depends on the number of disorder or missing residues). Then open Coot, use fit loop function to connect these two different chains.
pdb: "chain A" and "chain B". Each amino acid in a chain is called a residue, and they are numbered sequentially. Protein structures that are determined by NMR spectroscopy typically correspond to multiple structures in the PDB file. These structures are called models.
I've not done C++ for a long time but from this article, it appears that this is a performance trick to stop the recreation of symbols for common headers.
You could try /Z7 to embed info in each obj, and not create a PDB and then link and recreate it with a rebase as in this article.
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