I read that in pathlib we can create a child path by using / between two paths, where a comma would also work. However, I can't find out if there is a difference between the two cases. In the following example, the output is the same:
from pathlib import Path
p = Path('/hello', 'world')
s = Path(p, 'how', 'are', 'you')
ns = Path(p / 'how', 'are', 'you')
print(s)
print(ns)
But considering that pathlib is heavily object-oriented, I guess there might be something different behind the scenes. Is there a difference between using / in Path in contrast with a comma?
The whole point of using the / operator between pathlib.Path objects or a Path object with a str object is so you can avoid wrapping everything in calls to Path. 
>>> from pathlib import Path
>>> p = Path('/hello', 'world')
>>> p / 'how'
PosixPath('/hello/world/how')
>>> p / 'how' / 'are' / 'you'
PosixPath('/hello/world/how/are/you')
The distinction isn't between using "a comma" and a /, it's between using / and the constructor, Path.
I suppose, / is supposed to be similar to joinpath:
>>> p.joinpath('how','are','you')
PosixPath('/hello/world/how/are/you')
But somewhere under the hood you are creating a new Path instance, so Path is called anyway.
Note, from the docs:
When several absolute paths are given, the last is taken as an anchor (mimicking os.path.join()’s behaviour):
So they both have this behavior as well:
>>> '/etc' / p / '/usr'
PosixPath('/usr')
>>> Path('/etc', p, '/usr')
PosixPath('/usr')
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