Can I host an ASP.NET webite outside of IIS?

I need to write an ASP.NET application which must handle a very large number of transactions per second - as many as 5000 users may transact at the same time. I think I will use WCF in back to communicate with SQL server. But in front, can IIS handle 5000 users at the same time effectively, or is there any simple way to host my application outside of IIS?

Can asp net run without IIS?

An ASP.NET Core app can be hosted on Windows as a Windows Service without using IIS.

Can asp net run without server?

Yes, we can run an Asp.Net web application without web. config file but without in debugging mode. If we don't configure any settings in web. config file then it consider machine.

Can ASP Net Web API ability to both self hosting outside of IIS and IIS?

ASP.NET Web API can be either be hosted in IIS or in a separate host process.

It will depend on the characteristics of the machine but you could always setup a web farm to handle high loads.