So I am attempting to create the foundation for a basic 2D python game with X and Y movement using a sprite.
However the display is unresposive despite the code here attempting to screen.fill and screen.blit
playerX = 50
playerY = 50
player = pygame.image.load("player.png")
width, height = 64*8, 64*8
screen=pygame.display.set_mode((width, height))
screen.fill((255,255,255))
screen.blit(player, (playerX, playerY))
Am I missing something important?
A minimal, typical PyGame application
has a game loop
has to handle the events, by either pygame.event.pump() or pygame.event.get().
has to update the Surface whuch represents the display respectively window, by either pygame.display.flip() or pygame.display.update().
See pygame.event.get():
For each frame of your game, you will need to make some sort of call to the event queue. This ensures your program can internally interact with the rest of the operating system.
See also Python Pygame Introduction
Minimal example: 
 repl.it/@Rabbid76/PyGame-MinimalApplicationLoop
import pygame
pygame.init()
playerX = 50
playerY = 50
player = pygame.image.load("player.png")
width, height = 64*8, 64*8
screen = pygame.display.set_mode((width, height))
# main application loop
run = True
while run:
    # event loop
    for event in pygame.event.get():
        if event.type == pygame.QUIT:
            run = False
    # clear the display
    screen.fill((255,255,255))
    # draw the scene   
    screen.blit(player, (playerX, playerY))
    # update the display
    pygame.display.flip()
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