My Operating System is Win10-x64.
I run scrapy command: scrapy startproject tutorial in MS-DOS window then get the following error message:

I am sure i have installed scrapy, but any scrapy command is not working.
I notice the log: "from cryptography.hazmat.bindings._openssl import ffi, lib" and i seach the file cryptography.hazmat.bindings._openssl found it _openssl is a .pyd file.

it seems there is some error exist in this file.
I also notice that the OpenSSL package in Anaconda was built with vc9, I install the micro runtime environment and it didn't help me.
Try using the conda-forge channel which contains up to date packages.
conda install scrapy -c conda-forge
Note: Use a new environment as it's likely you installed cryptography (and possibly lxml) via pip, and that may not play well with a conda environments.
name = scrapy or cryptography
Just pip uninstall "name" as its likely for conda to tell you some of the uninstall cannot be done due to dependencies.
Thereafter pip install "name"
Problem is likely to be solved by now.
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